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GMBS，80307-12-6 ，98+異型蛋白交聯劑
GMBS，80307-12-6 ，98+異型蛋白交聯劑
產品名稱：GMBS
中文名稱：4-馬來酰亞胺基丁酸-N-琥珀酰亞胺酯
英文名稱：4-Maleimidobutyric acid N-hydroxysuccinimide ester
CAS #: 80307-12-6
簡介：GMBS is a non-cleavable heterobifunctional protein crosslinker. The GMBS crosslinking reagent is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The GMBS has a spacer arm length of 7.3 angstroms and is less immunogenic than the crosslinking analog MBS. The GMBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.
刺激是不可切割的異型蛋白交聯劑。的刺激是的交聯劑交聯的半抗原載體蛋白和抗體。的刺激有7.3埃的間隔臂的長度和較低的原性的化交聯。交聯劑的刺激的NHS酯和馬來酰亞胺基團的活性氨基和巰基moites反應。
Application
A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.
結構式：
Molecular Weight: 280.2
分子式 C12H12N2O6
CAS #: 80307-12-6
Spacer Length: 7.3 Å
Alternative Name: 4-Maleimdobutyric acid N-succinimidyl ester
純度：98%+
保存：-20℃
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