牛血清白蛋白 來(lái)源于牛血清

牛血清白蛋白 來(lái)源于牛血清

性質(zhì)

Related Categories Albumin, Bovine Serum Albumins,Chromatographically Purified, New Zealand Origin Bovine Serum Albumins, 生化試劑,
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biological source   bovine
assay   ≥98% (agarose gel electrophoresis)
form   lyophilized powder
mol wt   ~66 kDa
packaging   poly bottle of
impurities   ≤0.01% free fatty acid (GC)
pH   4.8-7.5
solubility   H2O: soluble 40 mg/mL
storage temp.   2-8°C

折疊

產(chǎn)品描述

包裝

1 kg in poly bottle

1, 25, 100 g in poly bottle

Preparation Note

Sourced and manufactured in New Zealand

prepared by chromatography

血清白蛋白可能也會(huì)被稱為Fraction V。該命名慣例取自使用冷乙醇沉淀對(duì)血清蛋白進(jìn)行分級(jí)的原始Cohn法。 血清白蛋白可在采用Cohn′s法的第五乙醇分級(jí)中發(fā)現(xiàn)。 從此，有些人便開始使用“Fraction V”這一術(shù)語(yǔ)來(lái)描述血清白蛋白，無(wú)論使用的是什么制備方法。 也有人在使用該術(shù)語(yǔ)來(lái)描述通過乙醇分級(jí)方法而純化得到血清白蛋白，而這種方法是相對(duì)于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生產(chǎn)和分銷從各種主要方法純化得到的血清白蛋白，包括真正的Cohn分級(jí)法、改良的乙醇分級(jí)方法、熱休克和色譜法。 更多的純化步驟包括結(jié)晶或木炭過濾。

Application

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry. [2]

Biochem/physiol Actions

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals. [1]

BSA的某些構(gòu)象和初級(jí)序列表位是人類對(duì)牛肉和牛奶過敏中的可疑過敏原。

General description

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein has an amazing ability to bind to ligands. [1]