| CBP73247 | |
| I. Introduction | |
Cell Line Name： | NACC2-NTRK2/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromucin |
Mycoplasma Status: | Negative |
| II.Background | |
NACC2, NACC family member 2, is the nucleus accumbens-associated protein 2 that functions as a transcriptional repressor and regulates Tp53, through Mdm2, to decrease cell proliferation (PMID: 22926524). An NACC2 fusion with NTRK2 has been observed in pilocytic astrocytoma (PMID: 23817572). | |
| III. Representative Data | |
1.NACC2-NTRK2/BaF3
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2. Anti-proliferation assay | |
Figure . Anti-proliferation assay of three reference compounds on the NACC2-NTRK2/BaF3 Stable Cell Line. | |
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