| CBP73320 | |
| I. Introduction | |
Cell Line Name： | SDC4-ROS1/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
| SDC4, syndecan 4, is a heparan sulfate proteoglycan that plays a role in intracellular signaling, including cell adhesion and cell-matrix interactions. SDC4 expression has been associated with breast cancer, a SDC4-ROS1 fusion has been identified in NSCLC and a SDC4-NRG1 fusion has been identified in lung adenocarcinoma and squamous cell carcinoma . | |
| III. Representative Data | |
1.Sanger of SDC4-ROS1/BaF3
| |
2. Anti-proliferation assay
Figure 2. CTG Proliferation Assay of BaF3 SDC4-ROS1 (C1). | |
化工儀器網