HVEM/U2OS Cell HVEM/U2OS Cell HVEM/U2OS Cell
| I. Background | |
皰疹病毒進入介質（HVEM），也稱為腫瘤壞死因子受體超家族成員 14 （TNFRSF14），是 TNF 受體（腫瘤壞死因子）超家族的人細胞表面受體。HVEM 在多種 免疫細胞中表達，包括 T 細胞、B 細胞、自然殺傷細胞、樹突狀細胞和內皮細胞。它還通 過在黑色素瘤細胞上的頻繁表達參與腫瘤的免疫逃避。 | |
| II. Introduction | |
| Expressed gene: | HVEM |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | Mccoy's5A+10%FBS+2 μg/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
Figure 1. Recombinant HVEM/U2OS Cell constitutively expressing HVEM. | |
Figure 2. Inhibtion of HVEM Induced SHP2 Recruitment In BTLA SHP2 Reporter Cell (C11) By Icatolimab with HVEM U2OS Cell (C7). | |
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