動脈粥樣硬化中血流紊亂會損害MerTK介導(dǎo)的主動脈內(nèi)皮細(xì)胞的胞葬作用2024/12/10

DisturbedflowimpairsMerTK-mediatedefferocytosisinaorticendothelialcellsduringatherosclerosisKeywords...

機(jī)械敏感的多囊蛋白1促進(jìn)骨膜干/祖細(xì)胞在骨折愈合中的骨軟骨分化2024/12/9

Mechanosensitiveproteinpolycystin-1promotesperiostealstem/progenitorcellsosteochondraldifferentiatio...

巨噬細(xì)胞極化通過調(diào)控細(xì)胞增殖、炎癥介質(zhì)與細(xì)胞外基質(zhì)代謝來調(diào)節(jié)椎間盤退變2024/12/3

Macrophagepolarizationregulatesintervertebraldiscdegenerationbymodulatingcellproliferation,inflammat...

Notch 下游 miR-342-5p 通過抑制 MYC 增強(qiáng)響應(yīng)剪切應(yīng)力的內(nèi)皮細(xì)胞動脈化2024/12/2

miR-342-5pdownstreamtoNotchenhancesarterializationofendothelialcellsinresponsetoshearstressbyrepress...

激活的SIRT1 通過增強(qiáng) H 型血管生成和骨形成的耦聯(lián)來促進(jìn)骨修復(fù)2024/11/26

SIRT1activationpromotesbonerepairbyenhancingthecouplingoftypeHvesselformationａndosteogenesisKWS：SIRT...

軟骨細(xì)胞生化介質(zhì)與機(jī)械轉(zhuǎn)導(dǎo)間相互作用揭示原發(fā)性膝關(guān)節(jié)骨關(guān)節(jié)炎中差異反應(yīng)2024/11/25

Theinterplaybetweenbiochemicalmediatorsａndmechanotransductioninchondrocytes:Unravellingthedifferenti...

CD97 在壓縮下通過 Rap1a/ERK 通路抑制破骨細(xì)胞分化2024/11/20

CD97inhibitsosteoclastdifferentiationviaRap1a/ERKpathwayundercompressionSubjectterms:Orthodontics,Ce...

Piezo1 介導(dǎo)的機(jī)械轉(zhuǎn)導(dǎo)導(dǎo)致血流紊亂誘導(dǎo)的動脈粥樣硬化內(nèi)皮炎癥2024/11/18

Piezo1‐MediatedMechanotransductionContributestoDisturbedFlow‐InducedAtheroscleroticEndothelialInflam...

B 細(xì)胞前體急性淋巴細(xì)胞白血病在骨髓間充質(zhì)基質(zhì)中引發(fā)干擾素-α/β 反應(yīng)2024/11/15

B-cellprecursoracutelymphoblasticleukemiaelicitsaninterferon-α/βresponseinbonemarrow-derivedmesenchy...

TNFSF12/TWEAK調(diào)節(jié)結(jié)腸炎性成纖維細(xì)胞分化促進(jìn)成纖維細(xì)胞-單核細(xì)胞相互作用2024/11/12

TheTNFSF12/TWEAKModulatesColonicInflammatoryFibroblastDifferentiationａndPromotesFibroblast-MonocyteI...

衰老誘導(dǎo)內(nèi)皮受損 金屬蛋白酶17 脫落連接粘附分子-A導(dǎo)致動脈重塑2024/10/28

Aging-inducedimpairedendothelialwallshearstressmechanosensingcausesarterialremodelingviaJAM-A/F11Rsh...

電壓門控性鈣通道α2δ亞基-1（CACNA2D1）調(diào)控結(jié)腸癌進(jìn)展并影響其微環(huán)境2024/10/28

CACNA2D1regulatestheprogressionａndinfluencesthemicroenvironmentofcoloncancerKeywords:CACNA2D1;Colonc...

人牙周膜的間充質(zhì)基質(zhì)細(xì)胞通過旁分泌和細(xì)胞接觸介導(dǎo)對 CD4+ T 的免疫調(diào)節(jié)2024/10/28

Paracrine-ａndcell-contact-mediatedimmunomodulatoryeffectsofhumanperiodontalligament-derivedmesenchym...

BACH1 基因的缺失通過減少內(nèi)皮炎癥減輕動脈粥樣硬化2024/10/28

DeletionofBACH1AttenuatesAtherosclerosisbyReducingEndothelialInflammationKeywords:BACH1;YAP;atherosc...

與體外循環(huán)相關(guān)的剪切應(yīng)力誘導(dǎo)單核細(xì)胞炎性細(xì)胞因子和壞死性凋亡的表達(dá)2024/10/25

Shearstressassociatedwithcardiopulmonarybypassinducesexpressionofinflammatorycytokinesａndnecroptosis...

流體剪切應(yīng)力通過NKG2D機(jī)械感應(yīng)增強(qiáng)自然殺傷細(xì)胞對循環(huán)腫瘤細(xì)胞的細(xì)胞毒性2024/10/25

Fluidshearstressenhancesnaturalkillercell'scytotoxicitytowardcirculatingtumorcellsthroughNKG2D-media...

骨細(xì)胞通過激活整合素α5調(diào)節(jié)雄性小鼠對機(jī)械負(fù)荷的骨合成代謝反應(yīng)2024/10/25

Osteocytesregulateboneanabolicresponsetomechanicalloadinginmalemiceviaactivationofintegrinα5Subjectt...

線粒體蛋白去琥珀?；揎椡ㄟ^調(diào)節(jié)線粒體穩(wěn)態(tài)介導(dǎo)壓縮誘導(dǎo)的椎間盤退變2024/10/25

SIRT5-relateddesuccinylationmodificationofAIFM1protectsagainstcompression-inducedintervertebraldiscd...

ChGn-2在急性壓力超負(fù)荷引起的心力衰竭中起心臟保護(hù)作用2024/9/29

心臟細(xì)胞外基質(zhì)（ECM）提供結(jié)構(gòu)支持并調(diào)節(jié)心臟中細(xì)胞因子和生長因子的活性。心臟ECM由膠原蛋白、糖蛋白、蛋白聚糖和糖胺聚糖組成，在心臟病進(jìn)展過程中經(jīng)歷了廣泛的重塑。硫酸軟骨素（CS）是主要的糖胺聚糖之...

暴露于機(jī)械線索的血管平滑肌細(xì)胞的表型狀態(tài)2024/9/29

在動脈粥樣硬化和其他心血管疾病的發(fā)展過程中，位于血管中膜的血管平滑肌細(xì)胞（SMCs）不斷從收縮狀態(tài)轉(zhuǎn)變?yōu)榕c分化的SMCs有很大差異的其他表型。該過程的特征是收縮性相關(guān)蛋白的表達(dá)減少或丟失，與其他細(xì)胞類...