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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

ADAMTS-1 Polyclonal Antibody detects endogenous levels of ADAMTS-1 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from ADAMTS-1 . at AA range: 160-240

Uniprot No

Q9UHI8

Alternative names

ADAMTS1; KIAA1346; METH1; A disintegrin and metalloproteinase with thrombospondin motifs 1; ADAM-TS 1; ADAM-TS1; ADAMTS-1; METH-1

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

ADAM metallopeptidase with thrombospondin type 1 motif 1(ADAMTS1) Homo sapiens This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008],

Other

ADAMTS1, A disintegrin and metalloproteinase with thrombospondin motifs 1

Mol.Wt (Da)

105358

Concentration

1 mg/ml