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Source

Rabbit

Applications

WB

Reactivity

Human, Mouse

Dilution

WB 1：500-2000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of ACTY at Human/Mouse

Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen

Synthesized peptide derived from human ACTY

Uniprot No

P42025

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],

Other

ACTR1B CTRN2, ACTY

Mol.Wt (Da)

41360

Concentration

1 mg/ml