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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Storage

-20°C/1 year

Specificity

ARBK1 Polyclonal Antibody detects endogenous levels of protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from human protein . at AA range: 1-80

Uniprot No

P25098

Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

G protein-coupled receptor kinase 2(GRK2) Homo sapiens The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

Other

ADRBK1 BARK BARK1 GRK2, Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)

Concentration

1 mg/ml