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BAP1 (phospho-Ser592) rabbit pAb
  • BAP1 (phospho-Ser592) rabbit pAb
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更新時間:2025-06-28 08:12:35

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  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human

  • Dilution

    WB 1:1000-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of Human BAP1 (phospho-Ser592)

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized phosho peptide around human BAP1 (Ser592)

  • Uniprot No

    Q92560

  • Alternative names

    Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    BRCA1 associated protein 1(BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],

  • Other

    BAP1 KIAA0272 hucep-6, BAP1 (Ser592)

  • Concentration

    1 mg/ml

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