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上海允麥生物科技有限公司
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- 麥經理
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Recombinant human WIF1
WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.
濃度：1mg/ ml
來源：Recombinant Human
純度：≥95% SDS-PAGE
表達系統：HEK 293 cells
標簽：His tag C-Terminus
蛋白長度：Full length protein
內毒素水平：<1.000 Eu/µg
純化方法：HPLC
應用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質期：1年
The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.
產品名稱：Rabbit Anti-WIF1 antibody
Rabbit Anti-WIF1
別名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.
來源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
反應：(predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量：39kDa
免疫原：KLH conjugated synthetic peptide derived from human WIF1
保存：-20℃
保質期：1年
產品名稱：Anti-WIF1 antibody
Mouse Anti-WIF1
別名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.
來源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
反應：Human
應用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應: Human
理論分子量：39kDa
免疫原：KLH conjugated synthetic peptide derived from human WIF1
保存：-20℃
保質期：1年
The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.
