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上海允麥生物科技有限公司
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Recombinant human WFS1 protein
DFNA14; DFNA38; DFNA6; DIDMOAD; WFRS; WFS; Wolfram syndrome 1 (wolframin); Wolfram syndrome; WOLFRAMIN; WFS1_HUMAN.
濃度：1mg/ ml
來源：Recombinant Human
純度：≥95% SDS-PAGE
表達系統：Escherichia coli
標簽：His tag
蛋白長度：Full length protein
內毒素水平：<1.000 Eu/µg
純化方法：HPLC
應用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質期：1年
WFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
產品名稱：Rabbit Anti-WFS1 protein antibody
Rabbit Anti-WFS1 protein
別名：DFNA14; DFNA38; DFNA6; DIDMOAD; WFRS; WFS; Wolfram syndrome 1 (wolframin); Wolfram syndrome; WOLFRAMIN; WFS1_HUMAN.
來源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
反應：Human (predicted: Mouse,Rat,Cow,Dog,Horse)
應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量：97kDa
免疫原：KLH conjugated synthetic peptide derived from human WFS1 protein
保存：-20℃
保質期：1年
產品名稱：Anti-WFS1 protein antibody
Mouse Anti-WFS1 protein
別名：DFNA14; DFNA38; DFNA6; DIDMOAD; WFRS; WFS; Wolfram syndrome 1 (wolframin); Wolfram syndrome; WOLFRAMIN; WFS1_HUMAN.
來源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
反應：Human
應用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應: Human
理論分子量：97kDa
免疫原：KLH conjugated synthetic peptide derived from human WFS1 protein
保存：-20℃
保質期：1年
Wolfram syndrome protein (WFS1) is an 890 amino acid protein that contains a cytoplasmic N-terminal domain, followed by nine-transmembrane domains and a luminal C-terminal domain. WFS1 is predominantly localized to the endoplasmic reticulum (ER) (1) and its expression is induced in response to ER stress, partially through transcriptional activation (2,3). Research studies have shown that mutations in the WFS1 gene lead to Wolfram syndrome, an autosomal recessive neurodegenerative disorder defined by young-onset, non-immune, insulin-dependent diabetes mellitus and progressive optic atrophy (4).
