聯系電話
上海允麥生物科技有限公司
中級會員·7年
- 聯系人：
- 麥經理
- 電話：
- 86-021-34553900
- 手機：
- 15121004110
- 傳真：
- 86-021-34553900
- 地址：
- 上海市青浦區
- 個性化：
- www.shymbio.com
- 網址：
- www.shymbio.com
掃一掃訪問手機商鋪
Recombinant human VAV3
Guanine nucleotide exchange factor VAV3; Protein vav 3; Protein vav3; VAV 3; Vav 3 guanine nucleotide exchange factor; VAV 3 oncogene; VAV 3 protein; VAV-3; VAV3 oncogene; VAV3 protein; VAV3_HUMAN.
濃度：1mg/ ml
來源：Recombinant Human
純度：≥95% SDS-PAGE
表達系統：Escherichia coli
標簽：His tag C-Terminus
蛋白長度：Full length protein
內毒素水平：<1.000 Eu/µg
純化方法：HPLC
應用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質期：1年
The Vav family of Rho guanine nucleotide exchange factors (GEFs) orchestrate signaling events following lymphocyte antigen receptor activation. Vav3, like Vav (also known as Vav1 or p95Vav), undergoes tyrosine phosphorylation downstream of T cell receptor cross-linkage, and subsequently interacts with 2 adaptor molecules, SLP76 and 3BP2. Following these events, however, the paths of Vav and Vav3 diverge; Vav affects IL-2 promotor activity, while Vav3 impacts gene transcription linked to serum response element (SRE). Furthermore, Vav3 expression follows a cell cycle-dependent pattern, with transient upregulation occuring during mitosis. Encforced Vav3 expression leads to the appearance of multinucleate cells, implicating a role for Vav3 in the control of cytokinesis.
產品名稱：Rabbit Anti-VAV3 antibody
Rabbit Anti-VAV3
別名：Guanine nucleotide exchange factor VAV3; Protein vav 3; Protein vav3; VAV 3; Vav 3 guanine nucleotide exchange factor; VAV 3 oncogene; VAV 3 protein; VAV-3; VAV3 oncogene; VAV3 protein; VAV3_HUMAN.
來源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應：Human,Rat (predicted: Mouse,Rabbit,Cow,Dog,Horse)
理論分子量：97kDa
免疫原：KLH conjugated synthetic peptide derived from human VAV3
保存：-20℃
保質期：1年
單克隆抗體
產品名稱：Anti-VAV3 antibody
Mouse Anti-VAV3
別名：Guanine nucleotide exchange factor VAV3; Protein vav 3; Protein vav3; VAV 3; Vav 3 guanine nucleotide exchange factor; VAV 3 oncogene; VAV 3 protein; VAV-3; VAV3 oncogene; VAV3 protein; VAV3_HUMAN.
來源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
應用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應: Human
理論分子量：97kDa
免疫原：KLH conjugated synthetic peptide derived from human VAV3
保存：-20℃
保質期：1年
The Vav family of Rho guanine nucleotide exchange factors (GEFs) orchestrate signaling events following lymphocyte antigen receptor activation. Vav3, like Vav (also known as Vav1 or p95Vav), undergoes tyrosine phosphorylation downstream of T cell receptor cross-linkage, and subsequently interacts with 2 adaptor molecules, SLP76 and 3BP2. Following these events, however, the paths of Vav and Vav3 diverge; Vav affects IL-2 promotor activity, while Vav3 impacts gene transcription linked to serum response element (SRE). Furthermore, Vav3 expression follows a cell cycle-dependent pattern, with transient upregulation occuring during mitosis. Encforced Vav3 expression leads to the appearance of multinucleate cells, implicating a role for Vav3 in the control of cytokinesis.
