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英文名稱：Azido-PEG8-acid

N3-PEG8-COOH

1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid

中文名稱：疊氮-八聚乙二醇-丙酸

CAS No.：1214319-92-2

MDL number:MFCD21363300

分子式：C19H37N3O10

分子量：467.5

純 度：95%+

結(jié)構(gòu)式：

產(chǎn)品簡介：

N3-PEG8-CH2CH2COOH，1214319-92-2，Azido-PEG8-acid是一種點(diǎn)擊化學(xué)試劑。分子一端的疊氮化物部分可用于銅（I）催化的點(diǎn)擊化學(xué)或無銅點(diǎn)擊化學(xué)。在分子另一端的疊氮化物部分和丙酸部分之間是單分子量的離散聚乙二醇（dPEG?）間隔基。丙酸部分可通過酰化反應(yīng)與伯胺或仲胺偶聯(lián)。

N3-PEG8-CH2CH2COOH，1214319-92-2，Azido-PEG8-acid contains an azide function on one end of a single molecular weight dPEG? spacer (32.2?) and a reactive group on the other end of the spacer. The dPEG? spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

其他同系列產(chǎn)品：

N3-PEG1-COOH  Azido-PEG1-acid   1393330-34-1

N3-PEG2-COOH  Azido-PEG2-acid   1312309-63-9

N3-PEG3-COOH  Azido-PEG3-acid   1056024-94-2

N3-PEG4-COOH  Azido-PEG4-acid   1257063-35-6

N3-PEG5-COOH  Azido-PEG5-acid   1425973-16-5

N3-PEG6-COOH  Azido-PEG6-acid   361189-66-4

N3-PEG8-COOH  Azido-PEG8-acid   1214319-92-2

N3-PEG9-COOH  Azido-PEG9-acid   1670249-37-2

N3-PEG10-COOH Azido-PEG10-acid    1644163-57-4

N3-PEG12-COOH Azido-PEG12-acid    1167575-20-3

N3-PEG24-COOH Azido-PEG24-acid    1167575-20-3

N3-PEG36-COOH Azido-PEG36-acid    1167575-20-3