細胞名稱

人視網(wǎng)膜上皮細胞ARPE-19

貨物編碼

BFN60807591

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研        2類

培養(yǎng)體系

90%DMEM+10%FBS+1%雙抗 

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡介

人視網(wǎng)膜上皮細胞ARPE-19取自19歲男性。該細胞源于ATCC。

注釋

Doubling time: 55 hours (from cell counting), 65 hours (from absorbance) (DOI=10.5897/IJBMBR2013.0154).

Omics: Deep proteome analysis.

Omics: Deep quantitative phosphoproteome analysis.

Omics: Metabolome analysis.

Omics: Transcriptome analysis.

Misspelling: APRE-19; Occasionally.

Derived from sampling site: Eye; retinal pigment epithelium.

基因突變

/

HLA信息

/

STR信息

Amelogenin        X,Y

CSF1PO        11

D2S1338        19

D3S1358        14,15

D5S818        13

D6S1043        17,19

D7S820        9,11

D8S1179        13

D12S391        21,22

D13S317        11,12

D16S539        9,11

D18S51        12,16

D19S433        12,13

D21S11        28,29

FGA        23

Penta D        11,13

Penta E        7,11

TH01        6,9.3

TPOX        9,11

vWA        16,19

參考文獻

PubMed=27499609

Wang Y., Sang A.-M., Zhu M.-H., Zhang G.-W., Guan H.-J., Ji M., Chen H.

Tissue factor induces VEGF expression via activation of the Wnt/beta-catenin signaling pathway in ARPE-19 cells.

Mol. Vis. 22:886-897(2016)

PubMed=28978645; DOI=10.1074/jbc.M117.812677

Chiang C.-K., Tworak A., Kevany B.M., Xu B., Mayne J., Ning Z., Figeys D., Palczewski K.

Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium.

J. Biol. Chem. 292:19826-19839(2017)

PubMed=29476476; DOI=10.1007/978-1-4939-7680-5_17

Fasler-Kan E., Aliu N., Wunderlich K., Ketterer S., Ruggiero S., Berger S., Meyer P.

The retinal pigment epithelial cell line (ARPE-19) displays mosaic structural chromosomal aberrations.

Methods Mol. Biol. 1745:305-314(2018)

PubMed=31254428; DOI=10.1111/ceo.13578

Churm R., Dunseath G.J., Prior S.L., Thomas R.L., Banerjee S., Owens D.R.

Development and characterization of an in vitro system of the human retina using cultured cell lines.

Clin. Exp. Ophthalmol. 47:1055-1062(2019)

PubMed=31412689; DOI=10.3390/pharmaceutics11080412

Hellinen L., Pirskanen L., Tengvall-Unadike U., Urtti A., Reinisalo M.

Retinal pigment epithelial cell line with fast differentiation and improved barrier properties.

Pharmaceutics 11:412.1-412.12(2019)