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目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B1823FITC Mouse Anti-Human CD206 Antibody (S-R575)

FITC Mouse Anti-Human CD206 Antibody (S-R575)
  • FITC Mouse Anti-Human CD206 Antibody (S-R575)
參考價(jià) 906
具體成交價(jià)以合同協(xié)議為準(zhǔn)
參考價(jià) 906
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 品牌 Starter/斯達(dá)特
  • 型號(hào) S0B1823
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 杭州市
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更新時(shí)間:2025-07-12 09:52:39瀏覽次數(shù):59評(píng)價(jià)

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FITC Mouse Anti-Human CD206 Antibody (S-R575)

CD206, also known as the mannose receptor (MRC1), is a highly glycosylated type I transmembrane protein primarily expressed on the surface of macrophages and dendritic cells. It plays a crucial role in the innate immune response by mediating the endocytosis and phagocytosis of various pathogens, including bacteria, fungi, and viruses, through its ability to bind to mannan-coated cell walls or envelopes. CD206 is a marker for alternatively activated M2 macrophages, which are characterized by their anti-inflammatory phenotype and are involved in wound healing and immune tolerance. In the context of cancer, tumor-associated macrophages often exhibit high levels of CD206, contributing to tumor progression by promoting immunosuppression, metastasis, and angiogenesis. This makes CD206 a potential target for cancer immunotherapy, as its activation can enhance both adaptive and innate antitumor immune responses.

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