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目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5143Biotin Rat Anti-Mouse CD24 Antibody (S-R671)

Biotin Rat Anti-Mouse CD24 Antibody (S-R671)
  • Biotin Rat Anti-Mouse CD24 Antibody (S-R671)
參考價 300
具體成交價以合同協議為準
參考價 300
具體成交價以合同協議為準
  • 品牌 Starter/斯達特
  • 型號 S0B5143
  • 廠商性質 生產商
  • 所在地 杭州市
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更新時間:2025-07-12 15:18:40瀏覽次數:38評價

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Biotin Rat Anti-Mouse CD24 Antibody (S-R671)

CD24, also known as the heat-stable antigen (HSA) or small-cell lung carcinoma cluster 4 antigen, is a highly glycosylated protein anchored to the cell membrane via glycosylphosphatidylinositol (GPI). It is a small mucin-like molecule expressed in various cell types, including B cells, immune cells, and tumor cells. CD24 acts as a "don't eat me" signal by interacting with Siglec-10 on macrophages, inhibiting phagocytosis and promoting immune evasion in cancer. This protein is overexpressed in many solid tumors, such as breast, lung, and colorectal cancers, and is associated with tumor progression and poor prognosis. Unlike CD47, CD24 is not expressed on red blood cells, making it a promising target for cancer immunotherapy without the risk of blood toxicity. Current research focuses on developing CD24-targeted therapies, including monoclonal antibodies and nanoparticle-based delivery systems, to enhance anti-tumor immunity.

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