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目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5308Alexa Fluor? 488 Rat Anti-Mouse CD4 antibody (S-1259-5)

Alexa Fluor? 488 Rat Anti-Mouse CD4 antibody (S-1259-5)
  • Alexa Fluor? 488 Rat Anti-Mouse CD4 antibody (S-1259-5)
參考價 863
具體成交價以合同協議為準
參考價 863
具體成交價以合同協議為準
  • 品牌 Starter/斯達特
  • 型號 S0B5308
  • 廠商性質 生產商
  • 所在地 杭州市
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更新時間:2025-07-12 21:01:35瀏覽次數:37評價

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Alexa Fluor? 488 Rat Anti-Mouse CD4 antibody (S-1259-5)

CD4 is a glycoprotein that functions as a co-receptor for the T-cell receptor (TCR) and is primarily expressed on the surface of helper T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily, consisting of four immunoglobulin domains (D1 to D4) that interact with MHC class II molecules on antigen-presenting cells. This interaction, mediated by the D1 domain of CD4, ensures that T cells recognize antigens presented by MHC II. The cytoplasmic tail of CD4 contains motifs that recruit the tyrosine kinase Lck, which amplifies T cell activation signals. Additionally, CD4 is crucial in the immune response, as it helps activate CD4+ T helper cells, which in turn stimulate other immune cells to combat infections. However, CD4 is also the primary receptor for HIV, allowing the virus to enter host T cells and cause immunodeficiency.

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