目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5332Alexa Fluor? 647 Mouse Anti-Human CD7 Antibody (S-575-58)
CD7, also known as GP40, is a transmembrane glycoprotein and a member of the immunoglobulin superfamily, primarily expressed on the surface of T cells and natural killer （NK） cells. It is highly expressed in acute T-cell leukemia （T-ALL） and certain peripheral T-cell lymphomas. CD7 plays a significant role in the regulation and activation of the immune system. It is involved in T-cell and T-cell/B-cell interactions during early lymphoid development and acts as a co-stimulatory molecule with CD3, CD45, and PI3K. CD7 has two known ligands, K12 protein and galectin-1, which can influence T cell proliferation, migration, and apoptosis. Additionally, CD7 is being explored as a target for cancer therapies, such as antibody-drug conjugates, due to its high expression in certain malignancies.
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