目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>病理/IHC抗體>> S0B2047EZH2 Recombinant Rabbit mAb(SDT-053-49)
Enhancer of zeste homolog 2 （EZH2） is a histone-lysine N-methyltransferase enzyme （EC 2.1.1.43） encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2 facilitates heterochromatin formation thereby silences gene function. Remodeling of chromosomal heterochromatin by EZH2 is also required during cell mitosis.
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