目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>病理/IHC抗體>> S0B2164CD19 Recombinant Rabbit mAb (SDT-164-33)
The CD19 antigen plays an important role in clinical oncology. In normal cells, it is the most ubiquitously expressed protein in the B lymphocyte lineage. CD19 expression is induced at the point of B lineage commitment during the differentiation of the hematopoietic stem cell, and its expression continues through preB and mature B cell differentiation until it is finally down-regulated during terminal differentiation into plasma cells. CD19 expression is maintained in B-lineage cells that have undergone neoplastic transformation, and therefore CD19 is useful in diagnosis of leukemias and lymphomas using monoclonal antibodies （mAbs） and flow cytometry [PMID: 8528044].
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