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目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>病理/IHC抗體>> S0B2268S-RMab? GST-π Recombinant Rabbit mAb (SDT-561-78)

S-RMab? GST-π Recombinant Rabbit mAb (SDT-561-78)
  • S-RMab? GST-π Recombinant Rabbit mAb (SDT-561-78)
參考價 600
具體成交價以合同協(xié)議為準
參考價 600
具體成交價以合同協(xié)議為準
  • 品牌 Starter/斯達特
  • 型號 S0B2268
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 杭州市
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更新時間:2025-07-14 07:41:47瀏覽次數(shù):38評價

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S-RMab? GST-π Recombinant Rabbit mAb (SDT-561-78)

Glutathione S-Transferases (GSTs) are members of the phase II detoxification enzyme family that conjugate glutathione to various electrophilic compounds, including metabolites generated by oxidative processes in the body, environmental toxins or carcinogens, and anti-cancer drugs. GSTP1 is a cytosolic protein that belongs to pi class of the GST superfamily. It is crystallized as a homodimer, but also exists in solution as an equilibrium mixture of monomer and dimer, depending on the protein concentration. Human GSTP1 is present at elevated levels in many tumor cells, and has unique properties as a cancer marker. Genetic polymorphisms and expression patterns of GSTP1 have been associated with a variety of effects on human cancer, anti-cancer drug resistance, and asthma. In addition to its role as a drug-metabolizing enzyme, GSTP1 has ligand binding properties and regulates kinase signaling pathways through protein-protein interactions.

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