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目錄:杭州斯達特生物科技有限公司>>蛋白>>細胞因子>> UA040015IL-1β Protein, Human

IL-1β Protein, Human
  • IL-1β Protein, Human
參考價 820
具體成交價以合同協議為準
參考價 820
具體成交價以合同協議為準
  • 品牌 Starter/斯達特
  • 型號 UA040015
  • 廠商性質 生產商
  • 所在地 南京市
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更新時間:2025-07-16 11:28:48瀏覽次數:53評價

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IL-1β Protein, Human

Interleukin-1β (IL-1β) is a major cytokine involved in monocyte activation and activation of proinflammatory signaling pathways in peripheral tissues and brain. IL-1β expression and its secretion are tightly regulated. IL-1β is released by several cell types, including activated macrophages, monocytes, and cells within the hypothalamus, where it can stimulate its own expression.IL-1β is present and active in the luteinized ovary as shown by its expression in human granulosa lutein cells and in follicular fluid macrophages that are natural components of the corpus luteum tissue. IL-1β, its corresponding receptor antagonist Interleukin Receptor Antagonist-1 (IL-1RA), and Interleukin 1 alpha (IL-1α) are encoded by the genes IL-1B, IL-1RN, and IL-1A respectively, as constituents of the Interleukin 1 (IL-1) gene cluster. IL-1β is a crucial candidate due to its dual role as both a proinflammatory signaling molecule and an inhibitor of gastric acid secretion. IL-1β can promote tumor growth, but also antitumor activities. The presence of IL-1β and other inflammatory cytokines also has been noted at an early phase of plaque formation in the brains of patients with Alzheimer's disease.

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